Yüklüyor......
Structural Perturbations Induced by the α-Anomer of the Aflatoxin B(1) Formamidopyrimidine Adduct in Duplex and Single-Strand DNA
[Image: see text] The guanine N7 adduct of aflatoxin B(1)exo-8,9-epoxide hydrolyzes to form the formamidopyrimidine (AFB-FAPY) adduct, which interconverts between α and β anomers. The β anomer is highly mutagenic in Escherichia coli, producing G → T transversions; it thermally stabilizes the DNA dup...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical Society
2009
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773149/ https://ncbi.nlm.nih.gov/pubmed/19831353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902052v |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|