Selective Incision of the α-N(5)-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV

Formamidopyrimidines (Fapy) lesions result from ring opening of the imidazole portion of purines. Fapy lesions can isomerize from the natural β-anomeric stereochemistry to the α-configuration. We have unambiguously demonstrated that the α-methyl-Fapy-dG (MeFapy-dG) lesion is a substrate for Escheric...

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Detalles Bibliográficos
Autores principales: Christov, Plamen P., Banerjee, Surajit, Stone, Michael P., Rizzo, Carmelo J.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925382/
https://ncbi.nlm.nih.gov/pubmed/20798848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/850234
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