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ATP Synthase Inhibition of Mycobacterium avium Is Not Bactericidal
The efficacy of ATP synthase inhibitor TMC207 was assessed in early and late Mycobacterium avium infections in mice. In contrast to what was earlier observed for M. tuberculosis, a bacteriostatic effect was obtained. In vitro, the minimal bactericidal concentration (MBC)/MIC ratio was very high. The...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology (ASM)
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772307/ https://ncbi.nlm.nih.gov/pubmed/19738016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00689-09 |
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