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Product Release Rather Than Chelation Determines Metal Specificity for Ferrochelatase
Ferrochelatase (protoheme ferrolyase, E.C. 4.99.1.1) is the terminal enzyme in heme biosynthesis and catalyzes the insertion of ferrous iron into protoporphyrin IX to form protoheme IX (heme). Within the past two years x-ray crystallographic data obtained with human ferrochelatase have clearly shown...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771925/ https://ncbi.nlm.nih.gov/pubmed/19703464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.042 |
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