Product Release Rather Than Chelation Determines Metal Specificity for Ferrochelatase

Ferrochelatase (protoheme ferrolyase, E.C. 4.99.1.1) is the terminal enzyme in heme biosynthesis and catalyzes the insertion of ferrous iron into protoporphyrin IX to form protoheme IX (heme). Within the past two years x-ray crystallographic data obtained with human ferrochelatase have clearly shown...

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Detaylı Bibliyografya
Asıl Yazarlar: Medlock, Amy E., Carter, Michael, Dailey, Tamara A., Dailey, Harry A., Lanzilotta, William N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771925/
https://ncbi.nlm.nih.gov/pubmed/19703464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.042
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