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Product Release Rather Than Chelation Determines Metal Specificity for Ferrochelatase

Ferrochelatase (protoheme ferrolyase, E.C. 4.99.1.1) is the terminal enzyme in heme biosynthesis and catalyzes the insertion of ferrous iron into protoporphyrin IX to form protoheme IX (heme). Within the past two years x-ray crystallographic data obtained with human ferrochelatase have clearly shown...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Medlock, Amy E., Carter, Michael, Dailey, Tamara A., Dailey, Harry A., Lanzilotta, William N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771925/
https://ncbi.nlm.nih.gov/pubmed/19703464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.042
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