Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are currently recognized as the most common genetic cause of parkinsonism. Among the large number of LRRK2 mutations identified to date, the G2019S variant is the most common. In Asia, however, another LRRK2 variant, G2385R, appears to occur...

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Detalhes bibliográficos
Main Authors: Ng, Chee-Hoe, Mok, Shaun Z. S., Koh, Cherlyn, Ouyang, Xuezhi, Fivaz, Marc L., Tan, Eng-King, Dawson, Valina L., Dawson, Ted M., Yu, Fengwei, Lim, Kah-Leong
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771772/
https://ncbi.nlm.nih.gov/pubmed/19741132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2375-09.2009
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