Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are currently recognized as the most common genetic cause of parkinsonism. Among the large number of LRRK2 mutations identified to date, the G2019S variant is the most common. In Asia, however, another LRRK2 variant, G2385R, appears to occur...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ng, Chee-Hoe, Mok, Shaun Z. S., Koh, Cherlyn, Ouyang, Xuezhi, Fivaz, Marc L., Tan, Eng-King, Dawson, Valina L., Dawson, Ted M., Yu, Fengwei, Lim, Kah-Leong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2009
Gaiak:
Brief Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771772/
https://ncbi.nlm.nih.gov/pubmed/19741132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2375-09.2009
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