Inclusion Body Formation and Neurodegeneration Are Parkin Independent in a Mouse Model of α-Synucleinopathy

Mutations in the genes coding for α-synuclein and parkin cause autosomal-dominant and autosomal-recessive forms of Parkinson's disease (PD), respectively. α-Synuclein is a major component of Lewy bodies, the proteinaceous cytoplasmic inclusions that are the pathological hallmark of idiopathic P...

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Publicado no:J Neurosci
Main Authors: von Coelln, Rainer, Thomas, Bobby, Andrabi, Shaida A., Lim, Kah Leong, Savitt, Joseph M., Saffary, Roya, Stirling, Wanda, Bruno, Kristy, Hess, Ellen J., Lee, Michael K., Dawson, Valina L., Dawson, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674122/
https://ncbi.nlm.nih.gov/pubmed/16597723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0414-06.2006
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