Loading...
Structurally Simple Inhibitors of Lanosterol 14α-Demethylase Are Efficacious In a Rodent Model of Acute Chagas Disease
We report structure-activity studies of a large number of dialkyl imidazoles as inhibitors of Trypanosoma cruzi lanosterol-14α-demethylase (L14DM). The compounds have a simple structure compared to posaconazole, another L14DM inhibitor that is an anti-Chagas drug candidate. Several compounds display...
Na minha lista:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771698/ https://ncbi.nlm.nih.gov/pubmed/19463001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900030h |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|