Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agents

New dialkylimidazole based sterol 14α-demethylase inhibitors were prepared and tested as potential anti-Trypanosoma cruzi agents. Previous studies had identified compound 2 as the most potent and selective inhibitor against parasite cultures. In addition, animal studies had demonstrated that compoun...

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Bibliografski detalji
Glavni autori: Suryadevara, Praveen Kumar, Racherla, Kishore Kumar, Olepu, Srinivas, Norcross, Neil R., Tatipaka, Hari Babu, Arif, Jennifer A., Planer, Joseph D., Lepesheva, Galina, Verlinde, Christophe L. M. J., Buckner, Frederick S., Gelb, Michael H.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111244/
https://ncbi.nlm.nih.gov/pubmed/24120539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.08.015
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