The p75 Neurotrophin Receptor Promotes Amyloid-β(1-42)-Induced Neuritic Dystrophy In Vitro and In Vivo

Oligomeric forms of amyloid-β (Aβ) are thought to play a causal role in Alzheimer's disease (AD), and the p75 neurotrophin receptor (p75(NTR)) has been implicated in Aβ-induced neurodegeneration. To further define the functions of p75(NTR) in AD, we examined the interaction of oligomeric Aβ(1-4...

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Main Authors: Knowles, Juliet K., Rajadas, Jayakumar, Nguyen, Thuy-Vi V., Yang, Tao, LeMieux, Melburne C., Vander Griend, Lilith, Ishikawa, Chihiro, Massa, Stephen M., Wyss-Coray, Tony, Longo, Frank M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771439/
https://ncbi.nlm.nih.gov/pubmed/19710315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0620-09.2009
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