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β-Amyloid(1–42) Induces Neuronal Death through the p75 Neurotrophin Receptor

Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic peptide Aβ, degeneration of the cholinergic innervation to the hippocampus (the septohippocampal pathway), and progressive impairment of cognitive function, particularly memory. Aβ is a ligand for the p75 neuro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Sotthibundhu, Areechun, Sykes, Alex M., Fox, Briony, Underwood, Clare K., Thangnipon, Wipawan, Coulson, Elizabeth J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670462/
https://ncbi.nlm.nih.gov/pubmed/18400893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0350-08.2008
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