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β-Amyloid(1–42) Induces Neuronal Death through the p75 Neurotrophin Receptor

Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic peptide Aβ, degeneration of the cholinergic innervation to the hippocampus (the septohippocampal pathway), and progressive impairment of cognitive function, particularly memory. Aβ is a ligand for the p75 neuro...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Sotthibundhu, Areechun, Sykes, Alex M., Fox, Briony, Underwood, Clare K., Thangnipon, Wipawan, Coulson, Elizabeth J.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670462/
https://ncbi.nlm.nih.gov/pubmed/18400893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0350-08.2008
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