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TRAF6 and p62 inhibit amyloid β-induced neuronal death through p75 neurotrophin receptor
Amyloid β (Aβ) aggregates are the primary component of senile plaques in Alzheimer disease (AD) patient’s brain. Aβ is known to bind p75 neurotrophin receptor (p75(NTR)) and mediates Aβ-induced neuronal death. Recently, we showed that NGF leads to p75(NTR) polyubiquitination, which promotes neuronal...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972807/ https://ncbi.nlm.nih.gov/pubmed/23017601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2012.09.005 |
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