p75 Neurotrophin Receptor Mediates Neuronal Cell Death by Activating GIRK Channels through Phosphatidylinositol 4,5-Bisphosphate

The pan neurotrophin receptor p75(NTR) signals programmed cell death both during nervous system development and after neural trauma and disease in the adult. However, the molecular pathways by which death is mediated remain poorly understood. Here, we show that this cell death is initiated by activa...

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Publicado en:J Neurosci
Autores principales: Coulson, Elizabeth J., May, Linda M., Osborne, Shona L., Reid, Kate, Underwood, Clare K., Meunier, Frederic A., Bartlett, Perry F., Sah, Pankaj
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2008
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671158/
https://ncbi.nlm.nih.gov/pubmed/18171948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2699-07.2008
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