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Contribution of individual histidines to the global stability of human prolactin
A member of the family of hematopoietic cytokines human prolactin (hPRL) is a 23k kDa polypeptide hormone, which displays pH dependence in its structural and functional properties. The binding affinity of hPRL for the extracellular domain of its receptor decreases 500-fold over the relatively narrow...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771294/ https://ncbi.nlm.nih.gov/pubmed/19384991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.100 |
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