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Analysis of Site-specific Histidine Protonation in Human Prolactin
The structural and functional properties of human prolactin (hPRL), a 23 kDa protein hormone and cytokine, are pH dependent. The dissociation rate constant for binding to the extracellular domain of the hPRL receptor increases nearly 500-fold over the relatively narrow and physiologic range from pH...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766358/ https://ncbi.nlm.nih.gov/pubmed/18652486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800444t |
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