Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models

The relation of α-synuclein (αS) aggregation to Parkinson's disease (PD) has long been recognized, but the mechanism of toxicity, the pathogenic species and its molecular properties are yet to be identified. To obtain insight into the function different aggregated αS species have in neurotoxici...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Karpinar, Damla Pinar, Balija, Madhu Babu Gajula, Kügler, Sebastian, Opazo, Felipe, Rezaei-Ghaleh, Nasrollah, Wender, Nora, Kim, Hai-Young, Taschenberger, Grit, Falkenburger, Björn H, Heise, Henrike, Kumar, Ashutosh, Riedel, Dietmar, Fichtner, Lars, Voigt, Aaron, Braus, Gerhard H, Giller, Karin, Becker, Stefan, Herzig, Alf, Baldus, Marc, Jäckle, Herbert, Eimer, Stefan, Schulz, Jörg B, Griesinger, Christian, Zweckstetter, Markus
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2009
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771093/
https://ncbi.nlm.nih.gov/pubmed/19745811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.257
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