Suppression of LPS-Induced TNF-α Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105

The activation of macrophages through Toll-like receptor (TLR) pathways leads to the production of a broad array of cytokines and mediators that coordinate the immune response. The inflammatory potential of this response can be reduced by compounds, such as prostaglandin E(2), that induce the produc...

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Main Authors: Wall, Estelle A., Zavzavadjian, Joelle R., Chang, Mi Sook, Randhawa, Baljinder, Zhu, Xiaocui, Hsueh, Robert C., Liu, Jamie, Driver, Adrienne, Bao, Xiaoyan Robert, Sternweis, Paul C., Simon, Melvin I., Fraser, Iain D. C.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770900/
https://ncbi.nlm.nih.gov/pubmed/19531803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000202
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