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Suppression of LPS-Induced TNF-α Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105

The activation of macrophages through Toll-like receptor (TLR) pathways leads to the production of a broad array of cytokines and mediators that coordinate the immune response. The inflammatory potential of this response can be reduced by compounds, such as prostaglandin E(2), that induce the produc...

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מידע ביבליוגרפי
Main Authors: Wall, Estelle A., Zavzavadjian, Joelle R., Chang, Mi Sook, Randhawa, Baljinder, Zhu, Xiaocui, Hsueh, Robert C., Liu, Jamie, Driver, Adrienne, Bao, Xiaoyan Robert, Sternweis, Paul C., Simon, Melvin I., Fraser, Iain D. C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770900/
https://ncbi.nlm.nih.gov/pubmed/19531803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000202
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