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Structure of D-AKAP2:PKA RI complex: Insights into AKAP specificity and selectivity
A-kinase anchoring proteins (AKAPs) regulate cyclic AMP-dependent protein kinase (PKA) signaling in space and time. Dual-specific AKAP 2 (D-AKAP2) binds to the dimerization/docking (D/D) domain of both RI and RII regulatory subunits of PKA with high affinity. Here, we have determined the structures...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090270/ https://ncbi.nlm.nih.gov/pubmed/20159461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.12.012 |
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