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Focal adhesion kinase modulates activation of NF-κB by flow in endothelial cells
Atherogenesis involves activation of NF-κB in endothelial cells by fluid shear stress. Because this pathway involves integrins, we investigated the involvement of focal adhesion kinase (FAK). We found that FAK was not required for flow-stimulated translocation of the p65 NF-κB subunit to the nucleus...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770750/ https://ncbi.nlm.nih.gov/pubmed/19587216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00226.2009 |
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