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JNK2 Promotes Endothelial Cell Alignment under Flow

Endothelial cells in straight, unbranched segments of arteries elongate and align in the direction of flow, a feature which is highly correlated with reduced atherosclerosis in these regions. The mitogen-activated protein kinase c-Jun N-terminal kinase (JNK) is activated by flow and is linked to inf...

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Detalhes bibliográficos
Main Authors: Hahn, Cornelia, Wang, Chong, Orr, A. Wayne, Coon, Brian G., Schwartz, Martin Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164210/
https://ncbi.nlm.nih.gov/pubmed/21909388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024338
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