Focal adhesion kinase modulates activation of NF-κB by flow in endothelial cells

Atherogenesis involves activation of NF-κB in endothelial cells by fluid shear stress. Because this pathway involves integrins, we investigated the involvement of focal adhesion kinase (FAK). We found that FAK was not required for flow-stimulated translocation of the p65 NF-κB subunit to the nucleus...

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Detalhes bibliográficos
Main Authors: Petzold, Tobias, Orr, A. Wayne, Hahn, Cornelia, Jhaveri, Krishna A., Parsons, J. Thomas, Schwartz, Martin Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770750/
https://ncbi.nlm.nih.gov/pubmed/19587216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00226.2009
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