Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity

Prdx6 (peroxiredoxin 6), a bifunctional protein with both GSH peroxidase and PLA(2) (phospholipase A(2)) [aiPLA(2) (acidic calcium-independent PLA(2))] activities, is responsible for the metabolism of lung surfactant phospholipids. We propose that the aiPLA(2) activity of the enzyme is regulated thr...

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Bibliographische Detailangaben
Hauptverfasser: Wu, Yongzheng, Feinstein, Sheldon I., Manevich, Yefim, Chowdhury, Ibrul, Pak, Jhang Ho, Kazi, Altaf, Dodia, Chandra, Speicher, David W., Fisher, Aron B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770719/
https://ncbi.nlm.nih.gov/pubmed/19140803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20082061
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