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Increased phospholipase A(2) activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein

We have shown previously and confirmed in the present study that the phospholipase A(2) (PLA(2)) activity of peroxiredoxin 6 (Prdx6) is markedly increased by phosphorylation. This report evaluated the conformation and thermodynamic stability of Prdx6 protein after phosphorylation to understand the p...

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Autori principali: Rahaman, Hamidur, Zhou, Suiping, Dodia, Chandra, Feinstein, Sheldon I., Huang, Shaohui, Speicher, David, Fisher, Aron B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447995/
https://ncbi.nlm.nih.gov/pubmed/22663767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300380h
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