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Oxidation of Peroxiredoxin 6 in the Presence of GSH Increases its Phospholipase A(2) Activity at Cytoplasmic pH

The expression of the phospholipase A(2) activity (aiPLA(2)) of peroxiredoxin 6 (Prdx6) in the cell cytoplasm is physiologically relevant for the repair of peroxidized cell membranes, but aiPLA(2) assay in vitro indicates that, unlike assay at pH 4, activity at cytosolic pH is essentially absent wit...

詳細記述

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書誌詳細
出版年:Antioxidants (Basel)
主要な著者: Zhou, Suiping, Dodia, Chandra, Feinstein, Sheldon I., Harper, Sandra, Forman, Henry J., Speicher, David W., Fisher, Aron B.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357108/
https://ncbi.nlm.nih.gov/pubmed/30586895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8010004
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