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Suppression of K(ATP) channel activity protects murine pancreatic β cells against oxidative stress
The enhanced oxidative stress associated with type 2 diabetes mellitus contributes to disease pathogenesis. We previously identified plasma membrane–associated ATP-sensitive K(+) (K(ATP)) channels of pancreatic β cells as targets for oxidants. Here, we examined the effects of genetic and pharmacolog...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2769178/ https://ncbi.nlm.nih.gov/pubmed/19805912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38817 |
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