Enhanced Glucose Tolerance by SK4 Channel Inhibition in Pancreatic β-Cells

OBJECTIVE: Ca(2+)-regulated K(+) channels are involved in numerous Ca(2+)-dependent signaling pathways. In this study, we investigated whether the Ca(2+)-activated K(+) channel of intermediate conductance SK4 (KCa3.1, IK1) plays a physiological role in pancreatic β-cell function. RESEARCH DESIGN AND...

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Main Authors: Düfer, Martina, Gier, Belinda, Wolpers, Daniela, Krippeit-Drews, Peter, Ruth, Peter, Drews, Gisela
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2009
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712794/
https://ncbi.nlm.nih.gov/pubmed/19401418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1324
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