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mTOR differentially regulates effector and regulatory T cell lineage commitment
Effector T cell differentiation requires the simultaneous integration of multiple, and sometimes opposing, cytokine signals. We demonstrate that mTOR plays a role in dictating the outcome of T cell fate. mTOR deficient T cells display normal activation and IL-2 production upon initial stimulation. H...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768135/ https://ncbi.nlm.nih.gov/pubmed/19538929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.04.014 |
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