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Memantine binding to a superficial site on NMDA receptors contributes to partial trapping

Although many nervous system disorders are associated with N-methyl-d-aspartate (NMDA) receptor overactivation, pharmacological inhibition of NMDA receptors has typically demonstrated limited clinical value due to debilitating psychotomimetic side-effects. Memantine, however, induces far fewer behav...

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Bibliografski detalji
Glavni autori: Kotermanski, Shawn E, Wood, Jesse T, Johnson, Jon W
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768015/
https://ncbi.nlm.nih.gov/pubmed/19687120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.176297
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