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Memantine binding to a superficial site on NMDA receptors contributes to partial trapping
Although many nervous system disorders are associated with N-methyl-d-aspartate (NMDA) receptor overactivation, pharmacological inhibition of NMDA receptors has typically demonstrated limited clinical value due to debilitating psychotomimetic side-effects. Memantine, however, induces far fewer behav...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768015/ https://ncbi.nlm.nih.gov/pubmed/19687120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.176297 |
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