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Memantine and Ketamine Differentially Alter NMDA Receptor Desensitization

Memantine and ketamine are clinically useful NMDA receptor (NMDAR) open channel blockers that inhibit NMDARs with similar potency and kinetics, but display vastly different clinical profiles. This discrepancy has been hypothesized to result from inhibition by memantine and ketamine of overlapping bu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Glasgow, Nathan G., Povysheva, Nadezhda V., Azofeifa, Andrea M., Johnson, Jon W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628409/
https://ncbi.nlm.nih.gov/pubmed/28877967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1173-17.2017
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