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Effects of memantine on the excitation-inhibition balance in prefrontal cortex

Memantine is one of the few drugs currently approved for treatment of Alzheimer’s disease (AD). The clinical effects of memantine are thought to be associated with inhibition of NMDA receptors (NMDARs). Surprisingly, other open-channel NMDAR blockers have unacceptable side effects that prevent their...

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Foilsithe in:Neurobiol Dis
Main Authors: Povysheva, Nadezhda V., Johnson, Jon W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102806/
https://ncbi.nlm.nih.gov/pubmed/27546057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.08.006
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