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Effects of memantine on the excitation-inhibition balance in prefrontal cortex

Memantine is one of the few drugs currently approved for treatment of Alzheimer’s disease (AD). The clinical effects of memantine are thought to be associated with inhibition of NMDA receptors (NMDARs). Surprisingly, other open-channel NMDAR blockers have unacceptable side effects that prevent their...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Povysheva, Nadezhda V., Johnson, Jon W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102806/
https://ncbi.nlm.nih.gov/pubmed/27546057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.08.006
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