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A mechanism for value-guided choice based on the excitation-inhibition balance in prefrontal cortex

Although the ventromedial prefrontal cortex (vmPFC) has long been implicated in reward-guided decision making, its exact role in this process has remained an unresolved issue. Here, we show that vmPFC levels of GABA and glutamate in human volunteers are predictive of both behavioural performance and...

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Detalhes bibliográficos
Main Authors: Jocham, Gerhard, Hunt, Laurence T, Near, Jamie, Behrens, Timothy EJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050076/
https://ncbi.nlm.nih.gov/pubmed/22706268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3140
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