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Mg(2+) Imparts NMDA Receptor Subtype Selectivity to the Alzheimer's Drug Memantine

N-Methyl-d-aspartate receptors (NMDARs) mediate interneuronal communication and are broadly involved in nervous system physiology and pathology (Dingledine et al., 1999). Memantine, a drug that blocks the ion channel formed by NMDARs, is a widely prescribed treatment of Alzheimer's disease (Sch...

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Detalhes bibliográficos
Main Authors: Kotermanski, Shawn E., Johnson, Jon W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679254/
https://ncbi.nlm.nih.gov/pubmed/19261873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3703-08.2009
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