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The superior folding of a RANTES analogue expressed in lactobacilli as compared to mammalian cells reveals a promising system to screen new RANTES mutants

Development of effective topical microbicides for the prevention of HIV-1 sexual transmission represents a primary goal for the control of the AIDS pandemic. The viral co-receptor CCR5, used by the vast majority of primary HIV-1 isolates, is considered a primary target molecule. RANTES and its deriv...

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Bibliographic Details
Main Authors: Secchi, Massimiliano, Xu, Qiang, Lusso, Paolo, Vangelista, Luca
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766862/
https://ncbi.nlm.nih.gov/pubmed/19573605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2009.06.018
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