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Rational Design of Novel HIV-1 Entry Inhibitors by RANTES Engineering
The discovery that the CC chemokines RANTES, MIP-1α and MIP-1β act as potent natural inhibitors of HIV-1, the causative agent of AIDS, and the subsequent identification of CCR5 as a major virus coreceptor have triggered a wealth of basic and applied research approaches aimed at developing safe and e...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2486335/ https://ncbi.nlm.nih.gov/pubmed/18243436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.12.023 |
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