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Rational Design of Novel HIV-1 Entry Inhibitors by RANTES Engineering

The discovery that the CC chemokines RANTES, MIP-1α and MIP-1β act as potent natural inhibitors of HIV-1, the causative agent of AIDS, and the subsequent identification of CCR5 as a major virus coreceptor have triggered a wealth of basic and applied research approaches aimed at developing safe and e...

詳細記述

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書誌詳細
主要な著者: Vangelista, Luca, Secchi, Massimiliano, Lusso, Paolo
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486335/
https://ncbi.nlm.nih.gov/pubmed/18243436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.12.023
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