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Mutational and energetic studies of Notch1 transcription complexes

Notch proteins constitute the receptors of a highly conserved signaling pathway that influences cell fate decisions both during development and in adults. A proteolytic cascade induced by ligand stimulation results in release of the Notch intracellular domain from the cell membrane, allowing it to e...

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Bibliografiske detaljer
Main Authors: Bianco, Cristina Del, Aster, Jon C., Blacklow, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766816/
https://ncbi.nlm.nih.gov/pubmed/18155729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.061
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