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Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription
Notch receptors control differentiation and contribute to pathologic states such as cancer by interacting directly with a transcription factor called CSL (for CBF-1/Suppressor of Hairless/Lag-1) to induce expression of target genes. A number of Notch-regulated targets, including genes of the hairy/e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892977/ https://ncbi.nlm.nih.gov/pubmed/17284587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611092104 |
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