Synthesis and Electrochemistry of 2-Ethenyl and 2-Ethanyl Derivatives of 5-Nitroimidazole and Antimicrobial Activity against Giardia lamblia

Infections with the diarrheagenic pathogen, Giardia lamblia, are commonly treated with the 5-nitroimidazole (5-NI) metronidazole (Mz), and yet treatment failures and Mz resistance occur. Using a panel of new 2-ethenyl and 2-ethanyl 5-NI derivatives, we found that compounds with a saturated bridge be...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Valdez, Carlos A., Tripp, Jonathan C., Miyamoto, Yukiko, Kalisiak, Jaroslaw, Hruz, Petr, Andersen, Yolanda S., Brown, Sabrina E., Kangas, Karina, Arzu, Leo V., Davids, Barbara J., Gillin, Frances D., Upcroft, Jacqueline A., Upcroft, Peter, Fokin, Valery V., Smith, Diane K., Sharpless, K. Barry, Eckmann, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766634/
https://ncbi.nlm.nih.gov/pubmed/19480409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900356n
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi