Impaired Parasite Attachment as Fitness Cost of Metronidazole Resistance in Giardia lamblia

Infections with the diarrheagenic protozoan pathogen Giardia lamblia are most commonly treated with metronidazole (Mz). Treatment failures with Mz occur in 10 to 20% of cases and Mz resistance develops in the laboratory, yet clinically, Mz-resistant (Mz(r)) G. lamblia has rarely been isolated from p...

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Detalhes bibliográficos
Main Authors: Tejman-Yarden, Noa, Millman, Maya, Lauwaet, Tineke, Davids, Barbara J., Gillin, Frances D., Dunn, Linda, Upcroft, Jacqueline A., Miyamoto, Yukiko, Eckmann, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186953/
https://ncbi.nlm.nih.gov/pubmed/21825286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00384-11
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