Deficiency of type I IFN receptor in lupus-prone NZM 2328 mice decreases dendritic cell numbers and activation and protects from disease

Type I interferons are potent regulators of innate and adaptive immunity and are implicated in the pathogenesis of systemic lupus erythematosus. Here we report that clinical and pathological lupus nephritis and serum anti-nuclear antibody levels are greatly attenuated in NZM 2328 mice deficient in t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Agrawal, Hemant, Jacob, Noam, Carreras, Esther, Bajana, Sandra, Putterman, Chaim, Turner, Sean, Neas, Barbara, Mathian, Alexis, Koss, Michael N., Stohl, William, Kovats, Susan, Jacob, Chaim O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766036/
https://ncbi.nlm.nih.gov/pubmed/19812195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803872
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