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Evidence of HIV-1 adaptation to host HLA alleles following chimp-to-human transmission
BACKGROUND: The cytotoxic T-lymphocyte immune response is important in controlling HIV-1 replication in infected humans. In this immune pathway, viral peptides within infected cells are presented to T-lymphocytes by the polymorphic human leukocyte antigens (HLA). HLA alleles exert selective pressure...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765438/ https://ncbi.nlm.nih.gov/pubmed/19818146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-164 |
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