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Evidence of HIV-1 adaptation to host HLA alleles following chimp-to-human transmission

BACKGROUND: The cytotoxic T-lymphocyte immune response is important in controlling HIV-1 replication in infected humans. In this immune pathway, viral peptides within infected cells are presented to T-lymphocytes by the polymorphic human leukocyte antigens (HLA). HLA alleles exert selective pressure...

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Bibliografische gegevens
Hoofdauteurs: Ngandu, Nobubelo K, Seoighe, Cathal, Scheffler, Konrad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765438/
https://ncbi.nlm.nih.gov/pubmed/19818146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-164
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