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The human insulin gene is part of a large open chromatin domain specific for human islets

Knowledge of how insulin (INS) gene expression is regulated will lead to better understanding of normal and abnormal pancreatic β cell function. We have mapped histone modifications over the INS region, coupled with an expression profile, in freshly isolated islets from multiple human donors. Unlike...

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Bibliografske podrobnosti
Main Authors: Mutskov, Vesco, Felsenfeld, Gary
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765094/
https://ncbi.nlm.nih.gov/pubmed/19805079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909288106
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