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The human insulin gene is part of a large open chromatin domain specific for human islets
Knowledge of how insulin (INS) gene expression is regulated will lead to better understanding of normal and abnormal pancreatic β cell function. We have mapped histone modifications over the INS region, coupled with an expression profile, in freshly isolated islets from multiple human donors. Unlike...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765094/ https://ncbi.nlm.nih.gov/pubmed/19805079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909288106 |
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