Evidence for a ferryl intermediate in a heme-based dioxygenase

In contrast to the wide spectrum of cytochrome P450 monooxygenases, there are only 2 heme-based dioxygenases in humans: tryptophan dioxygenase (hTDO) and indoleamine 2,3-dioxygenase (hIDO). hTDO and hIDO catalyze the same oxidative ring cleavage reaction of L-tryptophan to N-formyl kynurenine, the i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Lewis-Ballester, Ariel, Batabyal, Dipanwita, Egawa, Tsuyoshi, Lu, Changyuan, Lin, Yu, Marti, Marcelo A., Capece, Luciana, Estrin, Dario A., Yeh, Syun-Ru
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765089/
https://ncbi.nlm.nih.gov/pubmed/19805032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906655106
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki