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Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
We examined in HepG2 cells whether glucose-induced changes in AMP-activated protein kinase (AMPK) activity could be mediated by SIRT1, an NAD-dependent histone/protein deacetylase that has been linked to the increase in longevity caused by caloric restriction. Incubation with 25 vs. 5 mM glucose for...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764524/ https://ncbi.nlm.nih.gov/pubmed/19071085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.11.130 |
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