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Metabolic Adaptations through the PGC-1α and SIRT1 Pathways

Energy homeostasis in mammals is achieved through tight regulation of tissue-specific metabolic pathways that become dysregulated in metabolic diseases including diabetes and obesity. At the molecular level, main nutrient and hormonal signaling pathways impinge on expression of genes encoding for me...

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Autors principals: Rodgers, Joseph T., Lerin, Carles, Gerhart-Hines, Zachary, Puigserver, Pere
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275806/
https://ncbi.nlm.nih.gov/pubmed/18036349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.034
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