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Metabolic Adaptations through the PGC-1α and SIRT1 Pathways

Energy homeostasis in mammals is achieved through tight regulation of tissue-specific metabolic pathways that become dysregulated in metabolic diseases including diabetes and obesity. At the molecular level, main nutrient and hormonal signaling pathways impinge on expression of genes encoding for me...

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Detalhes bibliográficos
Main Authors: Rodgers, Joseph T., Lerin, Carles, Gerhart-Hines, Zachary, Puigserver, Pere
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275806/
https://ncbi.nlm.nih.gov/pubmed/18036349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.034
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