Nutrient-dependent Regulation of PGC-1α’s Acetylation State and Metabolic Function Through the Enzymatic Activities of Sirt1/GCN5

Mammals possess an intricate regulatory system for controlling flux through fuel utilization pathways in response to the dietary availability of particular macronutrients. Under fasting conditions, for instance, mammals initiate a whole body metabolic response that limits glucose utilization and fav...

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Autores principales: Dominy, John E., Lee, Yoonjin, Gerhart-Hines, Zachary, Puigserver, Pere
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886158/
https://ncbi.nlm.nih.gov/pubmed/20005308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.11.023
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