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Solution and Membrane-Bound Conformations of the Tandem C2A and C2B Domains of Synaptotagmin 1: Evidence for Bilayer Bridging
Synaptotagmin 1 (syt1) is a synaptic vesicle membrane protein that functions as the Ca(2+)-sensor in neuronal exocytosis. Here, site-directed spin labeling was used to generate models for the solution and membrane bound structures of a soluble fragment of syt1 containing its two C2 domains, C2A and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763419/ https://ncbi.nlm.nih.gov/pubmed/19501597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.06.007 |
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